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Computational model to reduce CRISPR-Cas9 off-target effects

We are pleased to announce our novel computational model for reducing off-target effects in CRISPR-Cas9 approaches: The manuscript Coupling Cas9 to artificial inhibitory domains enhances CRISPR-Cas9 target specificity by Aschenbrenner et al. got recently accepted and will be published in Scientific Advances
 
 
Aschenbrenner, S., Kallenberger, S., Hoffmann, M. D., Huck, A., Eils, R. & Niopek, D. (2020). Coupling Cas9 to artificial inhibitory domains enhances CRISPR-Cas9 target specificity. Science Advances, 6(6), doi:10.1126/sciadv.aay0187

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