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Research

Overview

HiDiH has had a long-standing interest in systems biology, -omics and big data analysis to gain better understanding into disease mechanisms and fundamental processes in molecular cell biology. We have been drivers of the International Cancer Genome Consortium (ICGC) since its inception. More recently, we have joined the worldwide effort to build a Human Cell Atlas by establishing the human pancreas cell atlas in health and disease. Here, we take particular advantage of our strong technology development arm in imaging and sequencing technology combined with our strengths in computational analysis of multi-dimensional data . Reaching out into the rich data world of clinical care, Roland Eils co-initiated the German Medical Informatics Initiative. Here, he has been the founder and coordinator of the HiGHmed consortium that integrates data from nine university medical centers in Germany with the goal to make data from clinical care and research interoperable across medical sectors and institutions. HiDiH integrates our research activities in fundamental life sciences and in innovative healthcare research at our two sites in Berlin and in Heidelberg.

Research Groups

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Artificial Intelligence

Roland Eils

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Computational Oncology

Naveed Ishaque

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Intelligent Imaging

Christian Conrad

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Health Data

Jürgen Eils & Harald Wagener

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Biomedical Genomics

Carl Hermann

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Synthetic Biology

Dominik Niopek

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Latest News

Martin Peuker: CIO of the year 2020

Charité CIO Martin Peuker is driving digitization in the healthcare sector with the Health Data Platform. The jury awards him 1st prize in the Public Sector category for his outstandig achievment. 

First Human Cell Atlas of the Pancreas on single-cell resolution

We are pleased to present our recent achievements in building the Human Cell Atlas of the Pancreas on single-cell resolution. Due to its high autolytic activities, the pancreas is a very challenging

Professor Dominik Niopek has been awarded the Life Science Bridge Award

Professor Dominik Niopek, Department of Biology at the TU, has been awarded the "Life Sciences Bridge - Aventis Foundation Postdoctoral Award" research prize sponsored by the Aventis Foundation. The

Computational model to reduce CRISPR-Cas9 off-target effects

We are pleased to announce our novel computational model for reducing off-target effects in CRISPR-Cas9 approaches: The manuscript Coupling Cas9 to artificial inhibitory domains enhances CRISPR-Cas9